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Field Notes

Precision and Accuracy in Medicine: the Case of “Ovarian” Cancer

While researching our new books on women’s and men’s cancers, we made a rather startling discovery: what everyone refers to as ovarian cancer doesn’t...

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The Hub

Revolutionizing Healthcare in British Columbia with Precision Medicine

Among the breath-taking backdrop of the Canadian Coast Mountains, an ecosystem is emerging in the province of British Columbia. But rather than one borne...

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SNPshot

The Earliest Genetic Snapshot: Non- Invasive Prenatal Testing Is Coming of Age

Today, more than one in five pregnant women in the US gets her blood drawn when she’s about ten weeks pregnant, not to gauge...

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Cognoscienti

Establishing The Promise Of Next Generation Sequencing: The Minnesota Guidelines

Unless a coherent and believable evidence base is established it is doubtful that the promise of precision medicine utilizing next generation sequencing (NGS) will...

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Precision Tools

Metastatic Melanoma: A New Era of Treatments

Historically, the prognosis for metastatic melanoma has been poor. Patients with metastatic disease have a median survival of 6-9 months and less than 10%...

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Field Notes

A Personalized Twist For Oncolytic Vaccines

Prospects for using viruses to fight cancer got a huge boost in late 2015 when the US Food and Drug Administration granted its first-of-a-kind...

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Cognoscienti

Precision Medicine Also Means An Excellent Diagnosis

I was recently introduced to a beautiful lady, immaculately dressed and wearing a wig. She told me she had cancer and was is in...

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Field Notes

PRECISION MEDICINE: The Center for Individualized Medicine, Mayo Clinic

In its 150-year history, the Mayo Clinic has stayed true to its patient-centered model of care. That same vision has guided the trajectory of...

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Setting the Stage – A Brief History of FDA Regulation of Precision Medicine, and a Glimpse to its Possible Future

Precision Medicine occupies a complex space – driven by science, dependent upon third parties for financial support, and bounded by vague and emerging laws...

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Field Notes

A Genomic Mandate

In 1989, a young man affected with hemochromatosis, a genetic disorder of iron metabolism, told this story: “I have been successfully treated with low...