Precision Medicine Quarterly
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PMLS
Novartis
Novartis

New Liquid Biopsy Method Infers RNA Expression From DNA Fragmentation Analysis

2022-04-08T20:30:02-05:00April 8th, 2022|

Researchers at Stanford University have developed a new method of detecting cancer from circulating tumor DNA (ctDNA) that combines DNA fragmentation analysis with deep sequencing to infer RNA expression profiles of tumor cells. The ability to predict RNA expression from ctDNA is a first for blood-based cancer detection, and has potential for diagnosis, prognosis, [...]

YESCARTA® RECEIVES U.S. FDA APPROVAL AS FIRST CAR T-CELL THERAPY FOR INITIAL TREATMENT OF RELAPSED OR REFRACTORY LARGE B-CELL LYMPHOMA (LBCL)

2022-04-03T09:52:15-05:00April 3rd, 2022|

Kite, a Gilead Company (Nasdaq: GILD), today announced the U.S. Food and Drug Administration (FDA) has approved Yescarta® (axicabtagene ciloleucel) CAR T-cell therapy for adult patients with large B-cell lymphoma that is refractory to first-line chemoimmunotherapy or that relapses within 12 months of first-line chemoimmunotherapy. Yescarta demonstrated a clinically meaningful and statistically significant improvement [...]

BabySeq Newborn Screening Project Aims For Increased Diversity in Second Phase

2022-04-03T09:46:26-05:00April 3rd, 2022|

BabySeq, the next-generation sequencing-based universal screening program for newborns, is gearing up for a second, expanded study. The lead researchers said they want the four-year, $5.1 million grant to help address a lack of diversity in the first cohort. The original BabySeq cohort was not diverse and thus the findings are not generalizable, according [...]

SomaLogic Previews New Products, Global Expansion Coming in 2022

2022-04-03T09:43:53-05:00April 3rd, 2022|

SomaLogic said this week that it expects to launch more than 10 new products over the course of the coming year, including diagnostic assays and distributed research kits. On a conference call with investors following the release of the firm's fourth quarter and full-year 2021 financial results, company officials previewed 2022 for the Boulder, [...]

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