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9 Essential Models to Predict the Future of Precision Medicine

As a quarter century follower of personalized medicine, the recent progress and pronouncements on precision medicine are greatly appreciated. Despite extraordinary complexities new ‘omics...

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Leveraging Blood-Based Biopsies

It is, without doubt, an exciting time to be an oncologist or a cancer researcher. As our understanding continues to grow of the underlying...

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Precision Medicine is a Value-of-Information Proposition – and Vice-Versa

In this inaugural issue of the Journal of Precision Medicine, we would like to draw attention to a decision-analytic concept that has grown prominent...

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Adding Value to Allele Data

In late winter at the Advances in Genome Biology and Technology (AGBT) scientific meeting in Marco Island, Fla., a coalition of 13 life science...

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A New Hope for Pancreatic Cancer

It’s a sad fact that most people diagnosed with pancreatic cancer feel their situation is hopeless. According to the National Cancer Institute, nearly 47,000...

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Precision Medicine: The Importance of Correctly Matching the Tool to the Task

his year, on April 16th the Personalized Medicine World Conference (PMWC) made its debut in the UK. Attendee’s benefited from new insights behind the...

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High Resolution: Bringing a Sharper Focus to Precision Medicine Through Design

With so much attention focused on new ways to collect, combine, and mine health data, it can be easy to overlook the critical need...

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Paths to Precision Medicine: A Perspective

Cancer is a complex, heterogeneous disease, driven by multiple molecular pathways. There are hundreds of known oncogenes, which arise in myriad combinations, making every...

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Human Genome Pioneer Continues to Push the Envelope

Say what you will about J. Craig Venter – and opinions run the gamut from him being our generation’s greatest scientist to him also...

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Precision Medicine: Too Much Precision, Not Enough Medicine?

“Precision Medicine,” a new name for “molecular medicine,” has been the goal of medicine since the time of the Greeks. Medicine without scientific precision...

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Why Do Physicians Experience Genomics Education Gaps, and What Can We Do About It?

Of the many factors needed for the complete clinical uptake of personalized medicine and its use to improve health out comes, one of the...

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Precision & Accuracy: A Way Forward in Cancer Medicine

We have reached a point where in the last 30 years your chance of surviving cancer has increased from 1 in 4 to roughly...

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Precise with Mice

A collaboration between the Jackson Laboratory (JAX) and six academic centers has garnered a five-year, $10 million grant from the National Institutes of Health...

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A Conversation with Werner Verbiest

Werner Verbiest has spent the better part of the last 25 years in roles focused on designing better diagnostics for a range of diseases....

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Waves of Precision Roll Into the Bay

Some life sciences clusters grow as a natural combination of academia and a critical mass of successful trailblazing companies. Others are built by intention...

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Personalized Health Care: Unlocking the Potential of Genomic and Precision Medicine

President Obama’s Precision Medicine Initiative has refocused national attention on the ability of genomics and other emerging technologies to provide a better understanding of...

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Are Payers Ready to Assess the Combined Value of Drugs with a Companion Diagnostic?

Targeted drugs that are tailored to biomarkers are most often developed or co-developed with a companion diagnostic to identify patients who are good responders....

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Methods Towards Clinical Actionability of Next Generation Sequencing

Precision Medicine necessitates continuously measuring the certainty with which the right patient receives the right treatment at the right time. Common clinical presentations are...

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Electronic Health Systems: Golden Mine for Precision Medicine?

Precision medicine is an emerging field whose relevance is destined to grow at a pace, that at least in part, depends on the concomitant...

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Blood-Based Companion Diagnostics

Since the seminal reports of the utility of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in evaluating a cancer patient’s response to...

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Epigenetic Therapies, Immune Therapies, and Anti-Angiogenic Therapies: The Triad of Oncology. Angiogenesis: Cause or effect?

Advances in technology have allowed medical providers to customize healthcare with medical decisions, practices, and therapeutics being tailored to the individual patient. Through the...

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Optimism and Purpose Drive Immune-Oncology Advances

It is, fair to say the field of immune-oncology is still in its infancy. But the concept of immune system activation as a means...

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Biotech Billionaire Dr. Patrick Soon-Shiong Brings Multidisciplinary Approach To Answering Biology’s Most Basic Questions.

When you hear Soon-Shiong elucidate his vision of the future of healthcare and the development of new therapeutics, the holistic approach he intends to...

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What’s in a Name? The Evolution of “P-Medicine”

The current paradigm of modern healthcare is a reactive response to patient symptoms, subsequent diagnosis and corresponding treatment of the specific disease(s). This approach...

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Precision Medicine in Infectious Diseases: Changing the treatment paradigm for bacterial infections to end the Antimicrobial Resistance Crisis.

Precision medicine is often associated with oncology where the ability to screen and select patients based on a particular mutation is critical for use and...

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