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Cognoscienti

Precision Medicine in Infectious Diseases: Changing the treatment paradigm for bacterial infections to end the Antimicrobial Resistance Crisis.

Precision medicine is often associated with oncology where the ability to screen and select patients based on a particular mutation is critical for use and...

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Precision Tools

Pharmacovigilance and Data for Precision Medicine.

There is plenty of chatter surrounding ‘data driven discovery’ currently, yet do those authors, bloggers and conference speakers all talk of the same thing? Could...

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Precision Tools

Cancer genome sequence data combined with incidence statistics suggests large numbers of patients could benefit from off-label therapies.

Targeted molecular therapies offer the hope that they can be used in any disease that carries the specific molecular aberration being targeted. Combining data on...

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Cognoscienti

Precision Diagnosis for Precision Medicine

The Precision Medicine Initiative and a “Moonshot to Cure Cancer” were announced by President Barack Obama in two consecutive State of the Union addresses in January...

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Precision Tools

Metabolomics, The Iceberg of Complexity and Clinical Utility

The genomic revolution continues to deliver research and clinical breakthroughs (CRISPR/Cas, WGS) that suggest greater precision and prediction is just ahead. And despite extraordinary complexities proteomics...

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Cognoscienti

Personalized Medicine at FDA: 2015 Progress Report

The transformation of health care from one-size-fits-all, trial-and-error medicine to a targeted approach utilizing an individual patient’s molecular information continues to accelerate as the U.S. Food...

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The Hub

Small in stature, Big in activity

It is well documented that within the historic walls of Cambridge University, Watson and Crick first made their discovery of the structure of DNA....

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Cognoscienti

The Complementary Iceberg Tips of Diabetes and Precision Medicine.

Diabetes is perceived as a “simple disease” and manifested in the form of inadequate blood glucose regulation. Paradoxically, it is now also recognized as a...

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Field Notes

Fine-tuning donor-patient organ matching

The International Genetics & Translational Research in Transplantation Network (iGENETRAiN) and commercial collaborator Affymetrix have together embarked on a genome-wide association study. The aim is to identify specific genetic variants that may...

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Field Notes

Finding the markers for a broken heart

PHOENIX – Research conducted at the Translational Genomics Institute (TGen) and the Barrow Neurological Institute has identified, for the first time, genes associated with stress-induced cardiomyopathy (SIC), a...

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20/20

Sequencing pioneer and serial entrepreneur Jonathan Rothberg continues his “wild ride”

Most 10 year old kids don’t grow up with the use a full chemistry lab in the basement and a copy of ‘Fortunes Formula’ to help...

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Field Notes

OME-ing in on precision wellness

Pathway Genomics’ OME personalized wellness app leverages Watson’s cognitive computing In early January at the Consumer Electronics Show in Las Vegas, Pathway Genomics announced the closed-alpha release of...

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SNPshot

CRISPR-Cas9: The bold, new, fast, inexpensive frontier of gene editing

If Helen of Troy possessed the face that launched a thousand ships, it is not a stretch to say that the publication in the summer...