News
Field Notes

Widening the Path of Precision Cancer Medicine

How DarwinHealth’s protein-hunting algorithms are helping the company advance cancer therapy and fill the gaps left by more traditional, gene-based methods

News
Precision Tools

Scaling-up NGS Secondary Analysis Using Field Programmable Gate Arrays in the Cloud

Next-generation sequencing (NGS) holds the promise of tailoring diagnosis and treatment to individuals based on their genetic makeup. As the price of sequencing drops,...

News
Precision Tools

Precision Oncology Trials: A Look Ahead

Life science sponsors are incorporating patient genetic and genomic information in clinical development programs to find the most accurate and effective treatments for patient...

News
Precision Tools

Unraveling the Microbiome’s Complex Role in Immunotherapy

A growing body of evidence has shown that the microbiome influences both the development of disease and patient response to therapy. In the field...

News
Cognoscienti

The Diagnostics Year In Review – 2017

2017 was an important year for Diagnostics’ impact on healthcare – marked by multiple positive milestones. While many of these milestones were overdue, we...

News
Cognoscienti

Are we at the Tipping Point for Precision Medicine IVD’s?

Medicine is full of examples of innovative and intuitively appealing ideas, some of which have really improved patients’ lives and some that just turned...

News
Cognoscienti

Regulatory Applications of Real World Evidence

Real-World Evidence (RWE) holds out the promise of reducing time and costs of product approvals, identifying new uses for existing products, increasing our ability...

News
Cognoscienti

Shifting Precision Medicine from Treating Cancer to Its Prevention: The HeritX Initiative

How a global collaborative effort and its Accelerated Roadmap to Prevention leverage BRCA gene mutations as the scientific gateway to cancer prevention

News
Cognoscienti

Thirty Years On, Quo Vadis Cancer Companion Diagnostics?

The concept of companion diagnostics for cancer was introduced in 1998 with approval of trastuzumab (Herceptin®) together with the respective HER2 test for selecting...

News
Cognoscienti

Breaking the Mold: FDA Pushes Towards Personal

In June, FierceBiotech reported that FDA would continue to “rethink targeted therapy regulation” to “speed development” in 2017. The agency certainly made good on...

News
Field Notes

Conference Report

There is a pressing need to better represent ethnic diversity with genomic resources — and in particular to do so in a way that...

News
Field Notes

The Precisionist

The trouble with the future is that it usually arrives before we are ready for it,”said 92-year old Arnold H. Glasow in 1995

News
Field Notes

The Olive – A Very Personal Medicine

I was once oblivious to the significance of the olive. As a child it was a color – a pastel shade of green –...

News
Field Notes

Deal or No Deal? Legal and Regulatory Considerations In the Business of Precision Medicine

Precision Medicine is rapidly taking a larger and larger share of new therapeutic product approvals as industry and the FDA are gaining a more...

News
Field Notes

Beyond The Economics

In a sense, when we have been talking about the goal of Precision Medicine, we have been discussing the value of diagnostics, with little...