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Cognoscienti

Towards Targeted Therapeutics: The Pharmaceutical Industry and Personalized Medicine

“The pharmaceutical industry is deeply committed to delivering on the promise of personalized medicine.” Ian Read, Pfizer CEO, National Press Club, Washington, DC, May 14, 2015.

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Cognoscienti

IMAGINARY WORLDS: REPRODUCIBILITY AND MODELED CLAIMS IN PRECISION MEDICINE

Developing decision models to support comparative cost-effectiveness claims is now an accepted standard in submissions both to gatekeepers for single payer health systems as well as...

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Field Notes

Glimpsing the future: New immune-based therapies for multiple myeloma.

Over the last year, the U.S. FDA approved a flurry of new drugs for use in multiple myeloma, a cancer that affects the bone...

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Precision Tools

The Computational Network Imaging Frontier: Relevance for Digital Biomarkers in Precision Oncology.

Cancer treatment is no doubt the greatest of the big challenges in the newborn field of Precision Medicine. As an effect of advances in imaging...

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Field Notes

The Mutual Benefits of Rare Disease Research and Precision Medicine

Precision medicine seems tailored to the study of rare diseases: at least 80 percent of them arise from genetic variations, and (though not always the case) show varying...

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Cognoscienti

The Silent Epidemic of Alzheimer’s Disease: Can Precision Medicine Provide Effective Drug Therapies?

Alzheimer’s disease is a complex, multi-faceted condition. Our understanding of the causal onset, diagnosis, progression, and treatment of the disease is limited and beset with...

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Field Notes

Diagnosing Rare Disease

A few days after the world celebrated Rare Disease Day, an international effort to raise awareness of rare diseases, UK-based Congenica, a company that offers clinical interpretation of genome sequence...

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Field Notes

Clinical Conundrums

Early this year, backed by a 3-year, $1.5-million grant from the Sohn Conference Foundation, Columbia University Medical Center announced plans to provide genome sequencing to...

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SNPshot

Prostate Cancer’s Precision Promise

If you’re a man living in the US today, you have a 1 in 7 chance of being diagnosed with prostate cancer before you die....