A Personalized Twist For Oncolytic Vaccines


Prospects for using viruses to fight cancer got a huge boost in late 2015 when the US Food and Drug Administration granted its first-of-a-kind approval of an oncolytic virus to treat advanced melanoma. Although the efficacy of the treatment, talimogene laherparepvec (T-VEC), was modest, its regulatory success has invigorated the field and dozens of other oncolytic viruses are now being tested in clinical trials.

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