Metabolon, Inc., the global leader in metabolomics solutions advancing a wide variety of research, diagnostic, therapeutic development, and precision medicine applications, today announced a joint development agreement with Mayo Clinic to develop novel metabolomic biomarker diagnostic tests. Metabolon will analyze Mayo Clinic patient clinical samples across multiple cohorts to look for disease biomarkers. New [...]

Bristol Myers Squibb (NYSE: BMY) and 2seventy bio, Inc. (Nasdaq: TSVT) today announced positive topline results from KarMMa-3, a Phase 3, global, randomized, multicenter, open-label study evaluating Abecma (idecabtagene vicleucel) compared to standard combination regimens in adults with multiple myeloma that is relapsed and refractory after two to four prior lines of therapy and [...]

Since its $400 million acquisition of telehealth platform developer and telepharmacy services company Lemonaid Health last November, 23andMe has started expanding beyond its core consumer genetic testing into a new business line called its genomic health service. "Developing our genomic health service for our customers remains a high priority for our consumer business," CFO [...]

A team from Germany, Slovenia, the Netherlands, UK, and US turned to single-cell gene expression profiling and other omics approaches to put together a "molecular map" of myocardial infarction effects — work that is expected to improve investigators' understanding of the coronary heart condition. With the help of spatial gene expression profiling, single-nucleus RNA [...]

The Beyond 1 Million Genomes Project has developed an assessment tool and guidelines to support European efforts to make at least a million human genomes available across the region in a secure way to researchers and specialized healthcare professionals. B1MG is an EU-funded effort that commenced in June 2020 and will run through May [...]

Invitae reported after the market close on Tuesday that its total second quarter revenues rose almost 18 percent year over year, to $136.6 million, just shy of analysts' estimate of $136.85 million, and driven largely by the company's oncology business. Invitae CFO Roxi Wen said on a conference call after the release of the [...]

10x Genomics said on Monday after the close of the market that it is lowering its 2022 revenue guidance by approximately $100 million. The Pleasanton, California-based single-cell and spatial omics analysis technologies firm now expects revenue in the range of $500 million to $520 million, representing growth of 2 percent to 6 percent over [...]

Researchers at Massachusetts General Hospital are developing a supportive care model to help advanced lung cancer patients better understand their prognosis after research showed that the optimism around precision oncology is making it difficult for oncologists and patients to have more sobering but realistic discussions about end-of-life decisions. The research, led by Laura Petrillo, [...]

Although few would argue there are challenges to equitably implementing precision cancer care, the barriers flagged by a doctor trying to deliver biomarker-informed treatments are quite different from those experienced by a patient trying to access genomic profiling and targeted therapies, and still different from the views of an insurance company executive tasked with [...]

MirXes, a Singapore-based RNA testing firm, said on Thursday it has signed a memorandum of understanding with several Singapore universities and hospitals to launch a study of circulating microRNA and DNA methylation biomarkers for multi-cancer early detection. Under Project CADENCE (cancer detected early can be cured), the partners plan to discover and validate methylation [...]